The biologically active iron chelators 2-pyridylcarboxaldehyde isonicotinoylhydrazone, 2-pyridylcarboxaldehyde benzoylhydrazone monohydrate and 2-furaldehyde isonicotinoylhydrazone.

Four nitrobenzaldehyde isonicotinoylhydrazones at 120 K: four different supramolecular structures in two and three dimensions.

The molecules of 2-nitrobenzaldehyde isonicotinoylhydrazone, C13H10N4O3, (I), are linked into a three-dimensional framework by a combination of one N-H...N and three C-H...O hydrogen bonds. In the isomeric compound 3-nitrobenzaldehyde isonicotinoylhydrazone, (II), the molecules are linked into complex sheets by a combination of three hydrogen bonds, one each of the N-H...N, C-H...N and C-H...O ...

Potent antimycobacterial activity of the pyridoxal isonicotinoyl hydrazone analog 2-pyridylcarboxaldehyde isonicotinoyl hydrazone: a lipophilic transport vehicle for isonicotinic acid hydrazide.

The rise in drug-resistant strains of Mycobacterium tuberculosis is a major threat to human health and highlights the need for new therapeutic strategies. In this study, we have assessed whether high-affinity iron chelators of the pyridoxal isonicotinoyl hydrazone (PIH) class can restrict the growth of clinically significant mycobacteria. Screening a library of PIH derivatives revealed that one...

A sensitive spectrophotometric method for the determination of titanium (IV) using gallacetophenone phenylhydrazone with applicatin to ilmenite

The most common spectrophotometric reagents employed for the determination of titanium (IV) are hydrogen peroxide[1] and tiron[2]. However, N-benzoylN-phenylhydroxylamine[3,4] and N-phenyllaurohydroxamic acid[5] are introduced for extractive spectrophotometric determination of titanium (IV). Aroylhydraones such as pyridoxal salicyloylhydrazone[6], diphenylglyoxal bis (benzoylhydrazone)[7] and d...

Potent Anti-Mycobacterial Activity of the Pyridoxal Isonicotinoyl Hydrazone Analogue, 2- Pyridylcarboxaldehyde Isonicotinoyl Hydrazone: A Lipophilic Transport Vehicle for Isonicotinic Acid Hydrazide

4,5-Diazafluorene-9-one Acylhydrazones and Their Lead(II) Complexes and the Crystal Structure of Hydrated 4,5-Diazafluorene-9-one 3-Methoxybenzoylhydrazone Supported by Extensive Hydrogen Bonds and Aromatic Ring Stacking Interactions

4,5-Diazafluorene-9-one acylhydrazone ligands: 4,5-diazafluorene-9-one 3-methoxy benzoylhydrazone (HL), 4,5-diazafluorene-9-one 2-thiopheneacetylhydrazone (HL) and 4,5-diazafluorene-9-one isonicotinoylhydrazone (HL) and their Pb(II) complexes PbL 2 1 2H2O 1, PbL (OAc) 2 and PbL 2 3 3 have been prepared and characterized by elemental analyses, molar conductivities, IR and H NMR spectroscopy. In ...